Penyakit jantung Koroner (PJK) dan Stroke adalah penyebab utama kematian di dunia. Secara Global 7,2 juta kematian berhubungan dengan PJK dan 5,7 juta berhubungan dengan Stroke. Penyebab kematian seseorang adalah karena pembuluh darah tersebumbat oleh endapan kolesterol.

Gejala :
1. Nyeri Dada
2. Sesak Nafas
3. Kelelahan
4. Palpitasi (Jantung Berdebar)
5. Pusing & Pingsan

Kadar Kolesterol LDL yang tinggi bukan merupakan satu-satunya penyebab terjadinya penyakit jantung koroner ataupun kematian, namun ada hal-hal lain yang terkait yakni Apolipoprotein A dan Apolipoprotein B,

Apa yang dimaksud Apo B
Apo B-100 (disebut juga Apolipoprotein B/Apo B) merupakan protein yang terlibat dalam metabolisme lipid dan merupakan unsur protein utama dari lipoprotein seperti LDL (veri Low Density Lipoprotein) dan LDl (Low Density Lipoprotein).
Apo B merupakan suatu parameter yang sangat menentukan terjadinya suatu endapan lemak, bila LDl Kolesterol rendah dan Apo B tinggi maka akan terjadi endapak lemak ( aterosklerosis). Rasio LDL-C Apo B dikenal sebagai small dense LDl (sd LDL).
Oleh sebab itu WHO menetapkan Apo-B sangat berperan pada resiko dini penyakit Jantung dan Pembuluh darah. Pada Pemeriksaan Apo B ini tidak memerlukan puasa dan biayanya relatif murah.

Nilai rujukan Apo B :
Pria : 66- 133 mg/dl
Wanita : 60 – 117 mg/dl

penyebabpenyakitjantungkoroner
Apa itu Apo A ?

Apo A memiliki dua bentuk utama, yaitu Apo A1 dan Apo A2. Apo A1 merupakan struktur apoprotein yang sangat penting bagi partikel HDL untuk melakukan proses Reverse Cholesterol Trasnsport (RCT). Adanya Apo A1 membuat HDL dapat keluar masuk ke dalam pembuluh darah untuk mengambil kelebihan kolesterol dan tidak ditahan oleh pembuluh darah. Pemeriksaan Apo A1 berguna juga didalam menilai kualitas partikel HDL karena Konsentrasi HDL yang tinggi belum tentu sebanding dengan konsentrasi Apo A1 yang tinggi. beberapa studi membuktikan anak-anak dari orang tua yang mengidap penyakit jantung korones, kadar Apo B tinggi tapi Apo A1 rendah walaupun LDL Kolesterol normal.

Nilai Apo A1 yang diharapkan:
– Pria : 104 – 202 mg/dl
– Wanita : 108-225 mg/dl

Penegahan :
Lemahnya perhatian terhadap faktor risiko dan penyakit, terbatasnya sarana pengobatan dan perawatan, dan tingginya biaya pengobatan merupakan hambatan yang mempengaruhi keberhasilan dalam
pengendalian faktor risiko dan PJK.
Beberapa strategi untuk menurunkan faktor resiko adalah sebagai berikut:
1. Membatasi akses produksi tembakau dengan meningkatkan pajak dan menegaskan larangan merokok.
2. Mengurangi penggunaan garam dalam makanan baik secara individu maupun di tempat makan atau restoran.
3. Mengurangi konsumsi gula dan lemak.
4. Meningkatkan aktivitas olahraga.

Penyakit Jantung Koroner

Comments

comments

17 gagasan untuk “Penyakit Jantung Koroner

  • 2 November 2016 pukul 13:00 am11
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    Hey there! Do you use Twitter? I’d like to follow you if that would be
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    Balas
    • 30 Mei 2018 pukul 13:00 am05
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      Hello, nice to e-meet you.
      Follow our social media on Twitter @kimiafarma_lab
      Thank you

      Balas
  • 23 November 2016 pukul 13:00 am11
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    Today, I went to the beach with my children. I found a sea shell and gave it to my 4 year old daughter and said “You can hear the ocean if you put this to your ear.” She put the shell to her ear and screamed.
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    Balas
  • 5 Desember 2016 pukul 13:00 pm12
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    This is a topic that’s near to my heart… Thank you!
    Where are your contact details though?

    Balas
    • 30 Mei 2018 pukul 13:00 am05
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      You are welcome.
      Follow our social media on Instagram @labkimiafarma , Facebook Lab Klinik Kimia Farma , Twitter @kimiafarma_lab

      Balas
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  • 21 November 2017 pukul 13:00 pm11
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    Writing a medical thesis or dissertation is a task done by almost all postgraduate and master’s medical students. Dissertation is derived from the Latin word disserto which means discuss. It is essential to write successful medical papers such as medicine essays and medical thesis papers. There are several reasons as to why students write medicine essays. One of the reasons is to promote enhancement of critical judgment, research skills as well as analytical skills. Moreover, medicine essay writing produce students with the ability to 4evaluate and analyze data critically.

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  • 29 Januari 2018 pukul 13:00 pm01
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    • 30 Mei 2018 pukul 13:00 am05
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  • 16 Juni 2018 pukul 13:00 pm06
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    Thanks-a-mundo for the article.Really looking forward to read more. Much obliged.

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  • 26 Juni 2018 pukul 13:00 pm06
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